State mortality · CDC NCHS 2017
Missouri - Mortality Statistics
46,763 deaths in 2017 across 10 tracked causes, at a state average age-adjusted rate of 61.7 per 100,000.
- 46,763
- Deaths, 2017
- Heart disease
- Leading cause
- +11%
- vs national avg
- 61.7
- Avg age-adj /100K
The verdict
Missouri's leading killer is heart disease at 191.1 per 100K (age-adjusted); the state's average age-adjusted rate across tracked causes runs 11% above the national figure.
- 191.1
- Heart disease /100K, leading
- +11%
- vs national avg rate
- -19.5%
- rate, 1999–2017
- 46,763
- total deaths, 2017
Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 2017. Age-adjusted rates allow fair comparison across states.
Where Missouri sits among all 51 states
Average age-adjusted death rate across the leading causes, 2017
61.7 Lower than 20% lower than 20% of 51 states
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS) · 2017
Missouri recorded 46,763 deaths in 2017 across 10 tracked causes (CDC WONDER · methodology). Total annual deaths rose from 45,434 in 1999 to 46,763 in 2017 (2.9%) — a modest trend over 18 years.
Leading cause: Heart disease with 14,820 deaths at 191.1 per 100,000 (age-adjusted). State avg age-adjusted rate 61.7 sits 11% above the 55.5 national figure.
Key Statistics
Top 5 Causes of Death
The five leading causes account for 38,666 deaths (82.7% of all deaths) in Missouri.
All Causes of Death in Missouri (2017)
| # | Cause of death | Deaths | % of total | Age-adj /100K |
|---|---|---|---|---|
| 1 | Heart disease | 14,820 | 31.7% | 191.1 |
| 2 | Cancer | 12,971 | 27.7% | 167.3 |
| 3 | CLRD | 3,940 | 8.4% | 50.7 |
| 4 | Unintentional injuries | 3,776 | 8.1% | 58.8 |
| 5 | Stroke | 3,159 | 6.8% | 41.0 |
| 6 | Alzheimer's disease | 2,545 | 5.4% | 32.3 |
| 7 | Diabetes | 1,605 | 3.4% | 21.0 |
| 8 | Kidney disease | 1,515 | 3.2% | 19.6 |
| 9 | Influenza and pneumonia | 1,281 | 2.7% | 16.7 |
| 10 | Suicide | 1,151 | 2.5% | 18.5 |
Mortality Trends Over Time
Total deaths and average age-adjusted rate across all causes, 1999–2017. Total deaths increased by 2.9% over this period.
Missouri — average age-adjusted death rate across all leading causes. Source: CDC WONDER (CDC NCHS / NVSS), 1999–2017.
| Year | Total Deaths | Avg Age-Adj Rate | YoY Change |
|---|---|---|---|
| 1999 | 45,434 | 76.6 | — |
| 2000 | 44,308 | 74.2 | -2.5% |
| 2001 | 44,092 | 73.1 | -0.5% |
| 2002 | 44,623 | 73.4 | +1.2% |
| 2003 | 44,410 | 72.3 | -0.5% |
| 2004 | 42,941 | 69.4 | -3.3% |
| 2005 | 43,267 | 69.0 | +0.8% |
| 2006 | 42,868 | 67.2 | -0.9% |
| 2007 | 42,409 | 65.5 | -1.1% |
| 2008 | 44,015 | 66.9 | +3.8% |
| 2009 | 42,276 | 63.4 | -4.0% |
| 2010 | 42,759 | 63.3 | +1.1% |
| 2011 | 42,725 | 62.0 | -0.1% |
| 2012 | 42,928 | 61.3 | +0.5% |
| 2013 | 43,884 | 61.5 | +2.2% |
| 2014 | 44,573 | 61.4 | +1.6% |
| 2015 | 45,567 | 61.9 | +2.2% |
| 2016 | 45,506 | 61.2 | -0.1% |
| 2017 | 46,763 | 61.7 | +2.8% |
National Comparison
How Missouri compares to the national average in 2017.
For Heart disease, Missouri ranks #11 out of 51 states (age-adjusted rate: 191.1 per 100,000). A higher rank indicates a higher mortality rate.
Nearby States & Comparisons
Similar and neighboring states most frequently compared with Missouri. Regional clusters tend to share environmental, economic, and healthcare-delivery conditions that drive correlated mortality patterns.
Arkansas
Leading cause: Heart disease · 223.8/100K
Illinois
Leading cause: Heart disease · 163.3/100K
Iowa
Leading cause: Heart disease · 167.4/100K
Kansas
Leading cause: Heart disease · 158.0/100K
Kentucky
Leading cause: Heart disease · 195.9/100K
Compare leading causes of death in Missouri →
Mortality figures drawn from CDC NCHS via CDC WONDER Underlying Cause of Death (NVSS). See methodology for data-vintage notes.
Neighboring States Comparison
Compare mortality data with states bordering Missouri (2017).
| State | Deaths (Top Cause) | Leading Cause | Age-Adj Rate |
|---|---|---|---|
| Missouri (this state) | 14,820 | Heart disease | 191.1 |
| Arkansas | 8,270 | Heart disease | 223.8 |
| Illinois | 25,394 | Heart disease | 163.3 |
| Iowa | 7,180 | Heart disease | 167.4 |
| Kansas | 5,723 | Heart disease | 158.0 |
| Kentucky | 10,343 | Heart disease | 195.9 |
| Nebraska | 3,581 | Heart disease | 149.3 |
| Oklahoma | 10,772 | Heart disease | 237.2 |
| Tennessee | 16,019 | Heart disease | 202.2 |
Dig deeper into Missouri's mortality data
Explore Missouri's causes of death, where it ranks nationally, and how it compares to other states.
All causes in Missouri
See every tracked cause of death in Missouri, ranked by deaths and age-adjusted rate.
Open the finder →Compare Missouri
Put Missouri side by side with up to three other states on any cause of death.
Compare states →National rankings
See where Missouri falls among all 50 states and DC on overall mortality.
View rankings →Heart disease by state
The leading cause nationwide — see how every state ranks on heart-disease deaths.
Heart disease →National trends, 1999-2017
How the leading causes of death shifted across the 19-year series.
See trends →Methodology & sources
How this CDC NCHS data is sourced, age-adjusted, and computed.
Read methodology →Related Guides
How to Read State Health Statistics
What age-adjusted death rates mean and why they matter for fair comparisons
Regional Health Disparities
Why mortality rates vary dramatically by region and the drivers behind these gaps
How Mortality Rates Have Changed
19-year analysis of which causes improved, which worsened, and what drove the shifts
Interpreting Mortality Trends in Missouri
Mortality data from the CDC WONDER database reveals how leading causes of death affect Missouri residents over time. Heart disease remains the leading cause, accounting for 14,820 deaths in 2017. Age-adjusted rates allow meaningful comparison between states and over time by accounting for differences in population age structure.
Missouri's average age-adjusted mortality rate of 61.7 per 100,000 is above the national average of 55.5, suggesting that residents face higher health risks compared to the country overall. Contributing factors can include access to care, chronic disease prevalence, and socioeconomic conditions. From 1999 to 2017, total deaths increased by 2.9%, a trend influenced by population growth, aging demographics, and shifts in disease patterns.
What the 2017 Missouri Mortality Record Shows
In 2017, CDC WONDER tallied 46,763 deaths in Missouri across 10 tracked cause-of-death categories. Heart disease led the record with 14,820 deaths at an age-adjusted rate of 191.1 per 100,000 — placing Missouri at #11 of 51 states for this cause, where a higher rank corresponds to a higher rate. The top five causes accounted for 38,666 deaths (82.7% of the state total), a concentration pattern consistent with national mortality profiles where a small number of chronic-disease categories dominate the annual record.
Missouri's average age-adjusted rate across all tracked causes was 61.7 per 100,000 — 11% above the national average of 55.5. An above-average state-level rate signals elevated mortality burden relative to the country overall, often correlating with a mix of chronic-disease prevalence, healthcare access gaps, smoking and obesity rates, and socioeconomic factors that vary by region. Over the 1999–2017 window, total deaths increased by 2.9%, and the state-wide average age-adjusted rate declined by 19.5% — a directional signal that integrates population growth, aging demographics, and shifts in disease patterns across the CDC WONDER record. Neighboring-state comparisons in the table above provide regional context, since states sharing geography often share environmental, economic, and healthcare-delivery conditions that drive correlated mortality patterns.
For planners, clinicians, and individual readers, the practical read of the 2017 Missouri record is layered: the state-wide average frames overall burden, the top-causes ranking identifies where the mortality load concentrates, and the multi-year trend indicates whether conditions are improving or worsening. Because age-adjusted rates use the year 2000 US standard population, differences between states and across years are not driven by demographic aging alone — they reflect real variation in exposure, prevention, and care delivery. These figures describe population-level mortality statistics and are not a substitute for medical advice; individual risk depends on personal health history, behaviors, and access to care. Consult a qualified healthcare professional about diagnosis, treatment, or prevention decisions. Data source: CDC National Center for Health Statistics, CDC WONDER Underlying Cause of Death, covering 1999–2017.
Frequently Asked Questions
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What the Missouri record means
Missouri's average age-adjusted rate runs 11% above the national figure — read the leading cause, the spread, and the trend together, not any single number.
- Heart disease is the leading cause at 191.1/100K — see how every state compares. Heart disease by state
- Put Missouri side by side with another state before drawing conclusions. Compare states
- The state-wide rate fell 19.5% from 1999 to 2017 — trends matter more than a single year. Mortality trends
Rates are age-adjusted to the 2000 U.S. standard population; the state average summarizes the leading causes, not all-cause mortality. Population statistics, not personal risk.
Rates are per 100,000 population. Age-adjusted rates use the year 2000 US standard population. Data covers 1999–2017. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS).
Read our methodology — how this data is sourced, computed, and verified.