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Cause of death · ICD-10 C00-C97 · 2017

Cancer - Death Rates by State

599,108 deaths in 2017 across 51 US states, with age-adjusted rates spanning 120.3–185.7 per 100,000.

599,108
Deaths, 2017
155.0
Avg age-adj /100K
154.2
Median /100K
51
States + DC

The verdict

Kentucky carries the nation's heaviest cancer burden at 185.7 per 100,000 - 1.5× the age-adjusted rate in Utah, the lowest.

185.7
Kentucky - highest, above average
120.3
Utah - lowest, well below average
#2 of 10
national rank by death toll
65.4
point spread, age-adjusted

ICD-10 C00-C97. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 2017.

Cancer accounted for 599,108 deaths across 51 US states in 2017. Age-adjusted rates range from 120.3 per 100,000 in Utah to 185.7 in Kentucky - a 65.4-point spread that reflects regional differences in healthcare access, lifestyle factors, and public health infrastructure. ICD-10 code: C00-C97. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS).

Nationally, cancer is the #2 leading cause of death - just behind heart disease.

Top 5 States by Cancer Rate

Top 5 States by Cancer Rate Horizontal bar chart of the top 5 items by value (per 100K). Top 5 States by Cancer Rate Top 5 1. Kentucky 185.7/100K 2. Mississippi 183.1/100K 3. West Virginia 179.4/100K 4. Oklahoma 177.3/100K 5. Louisiana 174.9/100K Source: CDC WONDER, 2017

How cancer mortality changed, 1999–2017

Between 1999 and 2017, US cancer deaths rose +9% from 549,838 to 599,108, while the average state age-adjusted rate fell −23% (201.5→155.0/100K).

Average of all 51 state age-adjusted rates per year. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 1999–2017.

140160180200220 1999200220052008201120142017 155
Average of all 51 state age-adjusted rates per year. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 1999–2017.

The line tracks the average state age-adjusted rate (unweighted across states), not a single national rate. Count and rate moved in opposite directions: total deaths climbed (+9%) while the age-adjusted rate fell (−23%) - a sign that population growth and aging, not worsening risk, drove the rising toll.

How the 51 states are spread on cancer

Kentucky (185.7) and Utah (120.3) sit at the extremes; the marker shows where the national average (155.0/100K) falls in the distribution.

Cancer age-adjusted rate distribution, 2017

All 51 states bucketed by rate, most cluster near the average, with a tail toward the high end

155.0 Lower than 55% lower than 55% of 51 states

120.0–129.0: 2 states (4%). Below this entry. 129.0–138.0: 4 states (8%). Below this entry. 138.0–147.0: 9 states (18%). Below this entry. 147.0–156.0: 14 states (27%). This entry sits in this band. 156.0–165.0: 10 states (20%). Above this entry. 165.0–174.0: 7 states (14%). Above this entry. 174.0–183.0: 3 states (6%). Above this entry. 183.0–192.0: 2 states (4%). Above this entry. US avg 120.0 192.0 every US state, bucketed by value

Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.

Source CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS) · 2017

States with Lowest Cancer Rates

The five states with the lowest age-adjusted death rates for cancer in 2017.

1. Utah 120.3/100K (-22% vs avg)
2. Hawaii 128.6/100K (-17% vs avg)
3. Colorado 131.0/100K (-15% vs avg)
4. Arizona 135.8/100K (-12% vs avg)
5. Wyoming 136.1/100K (-12% vs avg)

All State Rankings - Cancer (2017)

# State Deaths Age-Adjusted vs Avg
1 Kentucky 10,145 185.7 +20%
2 Mississippi 6,526 183.1 +18%
3 West Virginia 4,654 179.4 +16%
4 Oklahoma 8,203 177.3 +14%
5 Louisiana 9,513 174.9 +13%
6 Arkansas 6,517 173.6 +12%
7 Tennessee 14,302 173.4 +12%
8 Ohio 25,643 171.2 +10%
9 Maine 3,391 170.8 +10%
10 Indiana 13,462 170.0 +10%
11 Alabama 10,410 170.0 +10%
12 Missouri 12,971 167.3 +8%
13 Vermont 1,434 164.5 +6%
14 South Carolina 10,356 162.7 +5%
15 Michigan 20,671 161.3 +4%
16 Pennsylvania 28,387 161.0 +4%
17 Delaware 2,085 160.4 +3%
18 Iowa 6,449 158.0 +2%
19 Illinois 24,150 157.9 +2%
20 Kansas 5,494 157.2 +1%
21 North Carolina 19,474 157.1 +1%
22 South Dakota 1,715 156.9 +1%
23 Nevada 5,283 155.3 +0%
24 Georgia 17,135 154.9 -0%
25 Rhode Island 2,154 154.2 -1%
26 Oregon 8,083 154.2 -1%
27 New Hampshire 2,760 153.5 -1%
28 Wisconsin 11,318 153.2 -1%
29 Idaho 3,020 153.2 -1%
30 District of Columbia 1,031 152.8 -1%
31 Virginia 15,064 152.6 -2%
32 Nebraska 3,502 152.6 -2%
33 Montana 2,145 152.6 -2%
34 Maryland 10,796 151.5 -2%
35 Massachusetts 12,934 149.3 -4%
36 Washington 12,664 148.4 -4%
37 Minnesota 9,896 146.8 -5%
38 Texas 40,668 146.5 -5%
39 Florida 45,131 145.9 -6%
40 New Jersey 16,264 144.6 -7%
41 North Dakota 1,280 142.6 -8%
42 New York 34,956 141.2 -9%
43 Connecticut 6,608 139.6 -10%
44 Alaska 926 139.2 -10%
45 New Mexico 3,620 138.3 -11%
46 California 59,516 136.8 -12%
47 Wyoming 948 136.1 -12%
48 Arizona 12,008 135.8 -12%
49 Colorado 7,829 131.0 -15%
50 Hawaii 2,456 128.6 -17%
51 Utah 3,161 120.3 -22%

How do cancer death rates vary across states?

Cancer mortality data from the CDC WONDER database tracks deaths classified under ICD-10 code C00-C97 across all US states and territories. In 2017, this cause accounted for 599,108 deaths nationally.

The 65.4-point spread between the highest-rate state (Kentucky, 185.7/100K) and the lowest (Utah, 120.3/100K) reflects significant geographic variation. Age-adjusted rates use the year 2000 US standard population, enabling fair comparison between states with different demographic profiles. States above the national average of 155.0 per 100,000 may face higher risk factors related to healthcare access, environmental conditions, or socioeconomic disparities.

What the 2017 Cancer Record Shows

In 2017, CDC WONDER classified 599,108 deaths under ICD-10 code C00-C97 (Cancer) across 51 US states and territories, with age-adjusted rates ranging from 120.3 per 100,000 in Utah to 185.7 per 100,000 in Kentucky - a 65.4-point spread. The national average settled at 155.0 per 100,000 with a median of 154.2, and the 1.5x gap between extremes reflects how cancer mortality concentrates geographically rather than distributing evenly across the population.

The top-rate cluster, led by Kentucky, Mississippi, West Virginia - typically shares a recognizable pattern: higher prevalence of upstream risk factors, limited preventive-care infrastructure in rural areas, and uneven specialist access. The bottom-rate cluster - Utah, Hawaii, Colorado - tends to combine broader insurance coverage, stronger primary-care networks, and earlier detection pathways. Because rates are age-adjusted to the year 2000 US standard population, the gap is not an artifact of older populations in higher-rate states, it reflects real differences in underlying exposure, healthcare delivery, and socioeconomic conditions that persist across the 19-year CDC WONDER record (1999–2017).

For researchers, public-health planners, and individual readers, the practical read of the 2017 Cancer record is comparative: states above the 155.0 national average face elevated mortality burden relative to the country overall, while those below it show better outcomes on this specific cause, though a single-cause ranking does not capture a state's total health picture. These figures describe population-level mortality rates from a specific ICD-10 classification and are not a substitute for medical advice; individual risk depends on personal health history, behaviors, and access to care. Consult a qualified healthcare professional about diagnosis, treatment, or prevention decisions. Data source: CDC National Center for Health Statistics, CDC WONDER Underlying Cause of Death (ICD-10 code C00-C97).

Related causes of death frequently reviewed alongside cancer. Use the side-by-side comparison to see how rates, trends, and state rankings differ between causes.

Compare Cancer vs Heart disease →

All figures sourced from CDC NCHS via CDC WONDER Underlying Cause of Death (ICD-10). See the methodology page for file-by-file provenance.

Frequently Asked Questions

How many people die from cancer each year in the US?
In 2017, 599,108 deaths were attributed to cancer across all 51 US states and territories, with an average age-adjusted rate of 155.0 per 100,000 population.
Which state has the highest cancer death rate?
Kentucky has the highest age-adjusted death rate for cancer at 185.7 per 100,000 population (2017), with 10,145 total deaths.
Which state has the lowest cancer death rate?
Utah has the lowest age-adjusted death rate for cancer at 120.3 per 100,000 population (2017), with 3,161 total deaths.
What is the age-adjusted death rate and why does it matter?
The age-adjusted death rate accounts for differences in age distribution between states, making it possible to compare cancer mortality fairly. Without age adjustment, states with older populations would appear to have higher death rates simply due to demographics rather than actual health differences.
How wide is the gap between the highest and lowest cancer death rates?
The gap between the highest rate (Kentucky, 185.7/100K) and lowest rate (Utah, 120.3/100K) is 65.4 per 100,000, a 1.5x difference. This variation reflects differences in access to care, lifestyle factors, environmental conditions, and public health investment.
What years of cancer data are available?
Mortality data for Cancer is available from 1999 to 2017, covering 19 years of CDC WONDER data across all US states and territories.

What the cancer data shows

Kentucky carries the heaviest cancer burden - 1.5× the age-adjusted rate of Utah. Read the geography and the age adjustment together before drawing conclusions.

Age-adjusted rates use the 2000 U.S. standard population for fair cross-state comparison; figures are population statistics, not individual risk.

Rates are per 100,000 population. Age-adjusted rates use the year 2000 US standard population. ICD-10 code: C00-C97. Data covers 1999–2017. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS).

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the CDC WONDER database. Consult a qualified professional before making decisions based on this data.