Cause of death · ICD-10 C00-C97 · 2017
Cancer - Death Rates by State
599,108 deaths in 2017 across 51 US states, with age-adjusted rates spanning 120.3–185.7 per 100,000.
- 599,108
- Deaths, 2017
- 155.0
- Avg age-adj /100K
- 154.2
- Median /100K
- 51
- States + DC
The verdict
Kentucky carries the nation's heaviest cancer burden at 185.7 per 100,000 - 1.5× the age-adjusted rate in Utah, the lowest.
- 185.7
- Kentucky - highest, above average
- 120.3
- Utah - lowest, well below average
- #2 of 10
- national rank by death toll
- 65.4
- point spread, age-adjusted
ICD-10 C00-C97. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 2017.
Cancer accounted for 599,108 deaths across 51 US states in 2017. Age-adjusted rates range from 120.3 per 100,000 in Utah to 185.7 in Kentucky - a 65.4-point spread that reflects regional differences in healthcare access, lifestyle factors, and public health infrastructure. ICD-10 code: C00-C97. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS).
Nationally, cancer is the #2 leading cause of death - just behind heart disease.
Top 5 States by Cancer Rate
How cancer mortality changed, 1999–2017
Between 1999 and 2017, US cancer deaths rose +9% from 549,838 to 599,108, while the average state age-adjusted rate fell −23% (201.5→155.0/100K).
Average of all 51 state age-adjusted rates per year. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS), 1999–2017.
The line tracks the average state age-adjusted rate (unweighted across states), not a single national rate. Count and rate moved in opposite directions: total deaths climbed (+9%) while the age-adjusted rate fell (−23%) - a sign that population growth and aging, not worsening risk, drove the rising toll.
How the 51 states are spread on cancer
Kentucky (185.7) and Utah (120.3) sit at the extremes; the marker shows where the national average (155.0/100K) falls in the distribution.
Cancer age-adjusted rate distribution, 2017
All 51 states bucketed by rate, most cluster near the average, with a tail toward the high end
155.0 Lower than 55% lower than 55% of 51 states
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count, share, and where it sits relative to this entry.
Source CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS) · 2017
States with Lowest Cancer Rates
The five states with the lowest age-adjusted death rates for cancer in 2017.
All State Rankings - Cancer (2017)
| # | State | Deaths | Age-Adjusted | vs Avg |
|---|---|---|---|---|
| 1 | Kentucky | 10,145 | +20% | |
| 2 | Mississippi | 6,526 | +18% | |
| 3 | West Virginia | 4,654 | +16% | |
| 4 | Oklahoma | 8,203 | +14% | |
| 5 | Louisiana | 9,513 | +13% | |
| 6 | Arkansas | 6,517 | +12% | |
| 7 | Tennessee | 14,302 | +12% | |
| 8 | Ohio | 25,643 | +10% | |
| 9 | Maine | 3,391 | +10% | |
| 10 | Indiana | 13,462 | +10% | |
| 11 | Alabama | 10,410 | +10% | |
| 12 | Missouri | 12,971 | +8% | |
| 13 | Vermont | 1,434 | +6% | |
| 14 | South Carolina | 10,356 | +5% | |
| 15 | Michigan | 20,671 | +4% | |
| 16 | Pennsylvania | 28,387 | +4% | |
| 17 | Delaware | 2,085 | +3% | |
| 18 | Iowa | 6,449 | +2% | |
| 19 | Illinois | 24,150 | +2% | |
| 20 | Kansas | 5,494 | +1% | |
| 21 | North Carolina | 19,474 | +1% | |
| 22 | South Dakota | 1,715 | +1% | |
| 23 | Nevada | 5,283 | +0% | |
| 24 | Georgia | 17,135 | -0% | |
| 25 | Rhode Island | 2,154 | -1% | |
| 26 | Oregon | 8,083 | -1% | |
| 27 | New Hampshire | 2,760 | -1% | |
| 28 | Wisconsin | 11,318 | -1% | |
| 29 | Idaho | 3,020 | -1% | |
| 30 | District of Columbia | 1,031 | -1% | |
| 31 | Virginia | 15,064 | -2% | |
| 32 | Nebraska | 3,502 | -2% | |
| 33 | Montana | 2,145 | -2% | |
| 34 | Maryland | 10,796 | -2% | |
| 35 | Massachusetts | 12,934 | -4% | |
| 36 | Washington | 12,664 | -4% | |
| 37 | Minnesota | 9,896 | -5% | |
| 38 | Texas | 40,668 | -5% | |
| 39 | Florida | 45,131 | -6% | |
| 40 | New Jersey | 16,264 | -7% | |
| 41 | North Dakota | 1,280 | -8% | |
| 42 | New York | 34,956 | -9% | |
| 43 | Connecticut | 6,608 | -10% | |
| 44 | Alaska | 926 | -10% | |
| 45 | New Mexico | 3,620 | -11% | |
| 46 | California | 59,516 | -12% | |
| 47 | Wyoming | 948 | -12% | |
| 48 | Arizona | 12,008 | -12% | |
| 49 | Colorado | 7,829 | -15% | |
| 50 | Hawaii | 2,456 | -17% | |
| 51 | Utah | 3,161 | -22% |
How do cancer death rates vary across states?
Cancer mortality data from the CDC WONDER database tracks deaths classified under ICD-10 code C00-C97 across all US states and territories. In 2017, this cause accounted for 599,108 deaths nationally.
The 65.4-point spread between the highest-rate state (Kentucky, 185.7/100K) and the lowest (Utah, 120.3/100K) reflects significant geographic variation. Age-adjusted rates use the year 2000 US standard population, enabling fair comparison between states with different demographic profiles. States above the national average of 155.0 per 100,000 may face higher risk factors related to healthcare access, environmental conditions, or socioeconomic disparities.
What the 2017 Cancer Record Shows
In 2017, CDC WONDER classified 599,108 deaths under ICD-10 code C00-C97 (Cancer) across 51 US states and territories, with age-adjusted rates ranging from 120.3 per 100,000 in Utah to 185.7 per 100,000 in Kentucky - a 65.4-point spread. The national average settled at 155.0 per 100,000 with a median of 154.2, and the 1.5x gap between extremes reflects how cancer mortality concentrates geographically rather than distributing evenly across the population.
The top-rate cluster, led by Kentucky, Mississippi, West Virginia - typically shares a recognizable pattern: higher prevalence of upstream risk factors, limited preventive-care infrastructure in rural areas, and uneven specialist access. The bottom-rate cluster - Utah, Hawaii, Colorado - tends to combine broader insurance coverage, stronger primary-care networks, and earlier detection pathways. Because rates are age-adjusted to the year 2000 US standard population, the gap is not an artifact of older populations in higher-rate states, it reflects real differences in underlying exposure, healthcare delivery, and socioeconomic conditions that persist across the 19-year CDC WONDER record (1999–2017).
For researchers, public-health planners, and individual readers, the practical read of the 2017 Cancer record is comparative: states above the 155.0 national average face elevated mortality burden relative to the country overall, while those below it show better outcomes on this specific cause, though a single-cause ranking does not capture a state's total health picture. These figures describe population-level mortality rates from a specific ICD-10 classification and are not a substitute for medical advice; individual risk depends on personal health history, behaviors, and access to care. Consult a qualified healthcare professional about diagnosis, treatment, or prevention decisions. Data source: CDC National Center for Health Statistics, CDC WONDER Underlying Cause of Death (ICD-10 code C00-C97).
Related Causes & Comparisons
Related causes of death frequently reviewed alongside cancer. Use the side-by-side comparison to see how rates, trends, and state rankings differ between causes.
Heart disease
647,457 deaths nationally · avg rate 166.0/100K
Unintentional injuries
169,936 deaths nationally · avg rate 54.0/100K
CLRD
160,201 deaths nationally · avg rate 43.8/100K
Stroke
146,383 deaths nationally · avg rate 37.4/100K
Alzheimer's disease
121,404 deaths nationally · avg rate 32.1/100K
Compare Cancer vs Heart disease →
All figures sourced from CDC NCHS via CDC WONDER Underlying Cause of Death (ICD-10). See the methodology page for file-by-file provenance.
Explore cancer further
Look up cancer by state, compare states, or see how it fits the national picture.
Rank every state
Use the lookup tool to rank all 50 states and DC on cancer rates.
Open lookup →Compare states
Put up to four states side by side on cancer deaths and rates.
Compare states →All leading causes
Browse all 10 CDC NCHS leading causes of death and how they rank nationally.
All causes →National trends
See how cancer and the other leading causes changed, 1999-2017.
See trends →Related Guides
Leading Causes of Death in America
How the 10 leading causes rank, and what drives differences between states
Understanding Mortality Data
What CDC mortality statistics measure and how to interpret age-adjusted death rates
Regional Health Disparities
Why mortality rates vary dramatically by region and the drivers behind these gaps
Frequently Asked Questions
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What the cancer data shows
Kentucky carries the heaviest cancer burden - 1.5× the age-adjusted rate of Utah. Read the geography and the age adjustment together before drawing conclusions.
- Kentucky leads at 185.7/100K; see every state ranked by mortality rate. State rankings
- See how Cancer stacks up against Heart disease. Compare causes
- Heart disease is another leading cause worth examining alongside this one. View Heart disease
Age-adjusted rates use the 2000 U.S. standard population for fair cross-state comparison; figures are population statistics, not individual risk.
Rates are per 100,000 population. Age-adjusted rates use the year 2000 US standard population. ICD-10 code: C00-C97. Data covers 1999–2017. Source: CDC WONDER, Underlying Cause of Death (CDC NCHS / NVSS).
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from the CDC WONDER database. Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.